Interleukin‐10 modulates neuronal threshold of vulnerability to ischaemic damage
- 1 July 2000
- journal article
- research article
- Published by Wiley in European Journal of Neuroscience
- Vol. 12 (7) , 2265-2272
- https://doi.org/10.1046/j.1460-9568.2000.00090.x
Abstract
Interleukin‐10 (IL‐10) is a powerful suppressor of cellular immune responses, with a postulated role in brain inflammation. First, we have evaluated the role of this cytokine in ischaemic brain damag...Keywords
This publication has 33 references indexed in Scilit:
- Drug-Induced Neuroprotection From Global Ischemia Is Associated With Prevention of Persistent but Not Transient Activation of Nuclear Factor-κB in RatsStroke, 1998
- Differential effects of Th1 and Th2 derived cytokines on NGF synthesis by mouse astrocytesFEBS Letters, 1996
- Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses.Journal of Clinical Investigation, 1996
- Cytokines in inflammatory brain lesions: helpful and harmfulTrends in Neurosciences, 1996
- Interleukin-10 gene knock-out mice: a model of chronic inflammationClinical Immunology and Immunopathology, 1995
- Interleukin (IL)-10 Inhibits Nuclear Factor кB (NFкB) Activation in Human MonocytesJournal of Biological Chemistry, 1995
- Interleukin-10-deficient mice develop chronic enterocolitisCell, 1993
- Macrophage‐induced cytotoxicity of N‐methyl‐D‐aspartate receptor positive neurons involves excitatory amino acids rather than reactive oxygen intermediates and cytokinesEuropean Journal of Immunology, 1992
- Release of Endogenous and Newly Synthesized Glutamate and of Other Amino Acids Induced by Non‐N‐Methyl‐D‐Aspartate Receptor Activation in Cerebellar Granule Cell CulturesJournal of Neurochemistry, 1991
- Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.Stroke, 1986