Passive Immunization of Birds Against Malaria

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Abstract
Ducklings were immunized passively against blood-induced infection with Plasmodium lophurae by injn. of immune serum from ducks which had undergone several blood-induced infections with P. lophurae. Parasitized duck erythrocytes suspended in vitro in such immune serums were much less infectious for ducklings than parasitized erythrocytes suspended in normal duck serum. Although these serums seemed to contain agglutinins for P. lophurae. they also agglutinated normal duck erythrocytes, and the in vitro protective activity of a serum could be absorbed out by contact with lysed normal duck erythrocytes. Therefore it was thought that much of the protective action of these serums was produced by antibodies to duck erythrocytes. In keeping with the antigenic similarity of duck and chicken erythrocytes, these immune duck serums acting in vitro could reduce the infectivity for chicks of chicken erythrocytes infected with P. gallinaceum.
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