Growth and cell division during nitrogen starvation of the yeast Saccharomyces cerevisiae

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Abstract
During N starvation, cells of the yeast S. cerevisiae increased 3-fold in number, and little RNA and protein were accumulated. Both RNA and protein were extensively degraded during starvation, suggesting that intracellular macromolecules could supply most of the growth requirements. The types and proportions of stable RNA synthesized during N deprivation were characteristic of exponentially growing cells; however, the complement of proteins synthesized was different. Apparently once events in the DNA division cycle are initiated, cells can complete division with little dependence on continued net cell growth.