Abstract
The unexpected death of a young infant previously well or ill with a minor respiratory infection occurs with considerable frequency. Sudden unexpected death (SUD) is estimated to account for 15,000 fatalities per year in the United States, or twice the number caused by congenital abnormalities. In Cleveland, with a population of approximately 1.8 million, there are about 100 such cases a year. This loss of young lives with no apparent cause has provoked numerous hypotheses which, as Shaw states in a recent communication in theAmerican Journal of Diseases of Children,1"are in large part speculative and unproven." There are several observations common to most studies of the SUD syndrome; these must include the clues to its etiology and must fit any explanation: (1) Infants are usually between 2 weeks and 6 months of age, with a peak incidence at age 3 to 4 months. (2) Deaths occur in

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