Experimental design based 3-D QSAR analysis of steroid-protein interactions: Application to human CBG complexes
- 1 December 1990
- journal article
- conference paper
- Published by Springer Nature in Journal of Computer-Aided Molecular Design
- Vol. 4 (4) , 381-389
- https://doi.org/10.1007/bf00117403
Abstract
An experimental design based 3-D QSAR analysis using a combination of principal component and PLS analysis is presented and applied to human corticosteroid-binding globulin complexes. The predictive capability of the created model is good. The technique can also be used as guidance when selecting new compounds to be investigated.Keywords
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