MEDIASTINAL MASS WITH ACUTE-LEUKEMIA - MYELOBLASTOMA MASQUERADING AS LYMPHOBLASTIC LYMPHOMA

  • 1 January 1981
    • journal article
    • research article
    • Vol. 105  (3) , 126-129
Abstract
Acute leukemia of myeloblastic or myelomonocytic type after non-Hodgkin''s lymphoma is a recognized complication of radiotherapy or chemotherapy. A few reports suggest spontaneous development of, or coexistent, acute myeloblastic or myelomonocytic leukemia in patients with non-Hodgkin''s lymphoma, unrelated to therapy. A [human] case is presented which was initially interpreted as being lymphoblastic lymphoma with spontaneous acute leukemia but subsequently shown by cytochemical and ultrastructural studies to be myeloblastoma. The previously reported cases of non-Hodgkin''s lymphoma with spontaneous myeloid leukemia were reviewed in the light of these findings and such cases may, in fact, represent myeloblastomas (granulocytic sarcomas) rather than non-Hodgkin''s lymphoma.