Vimentin expression by reed-Sternberg cells in Hodgkin's disease
- 1 January 1992
- journal article
- Published by Springer Nature in Virchows Archiv
- Vol. 421 (1) , 9-11
- https://doi.org/10.1007/bf01607132
Abstract
The expression of vimentin in Reed-Sternberg cells in 61 samples of Hodgkin's disease (HD) was examined using an avidin-biotin-peroxidase complex technique. Forty biopsies (66%) expressed vimentin, and expression was seen in all subtypes of HD. No immunophenotypic differences between vimentin-positive and vimentin-negative cases were noted. The significance of such expression is unclear, but may be related to the alterations in growth and differentiation that are typical of neoplastic cells.Keywords
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