Alterations in cat cerebrocortical capillary morphometrical parameters following K+-induced cerebrocortical swelling

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Abstract
Histochemical, electron microscopic, and morphometrical techniques were employed in the determination of the effects attributed to K+-induced cerebrocortical swelling on cat cerebrocortical capillary diameter, length, surface area, volume, and minimal intercapillary distance. Bilaterally exposed and intact temporoparietal cerebral cortices of 4 conditioned adult cats were simultaneously superfused with isotonic, artificial CSF containing 3.5 mM K+ (control) and 54 mM K+ (experimental) for 1 h at 37°C with monitoring of systemic vital function, hematocrit, arterial blood gases, and determination of cerebrocortical tissue water content. The mean values for cerebrocapillary diameter were 5% (PP+-induced cerebrocortical swelling.