THE EFFECT OF SMALL AMOUNTS OF ADRENALIN UPON THE GLOMERULAR BLOOD VESSELS OF THE FROG'S KIDNEY PERFUSED AT CONSTANT RATE

Abstract
Frog kidneys were perfused with frog''s blood by means of an apparatus which insured constancy of blood flow. The side tube of the perfusion cannula was connected with a membrane manometer and a drop recorder adjusted to record outflow from the postcaval vein. The frog board was arranged on the stage of a microscope to which was attached a photomicrographic camera fitted with a demonstration ocular. The microscope was focused upon 1 glomerulus, and pictures were made as rapidly as plates could be changed. The substitution of blood containing a concentration of approximately 1500,000 adrenalin for normal blood caused the perfusion pressure to rise and the glomerular tufts to swell. The result is interpreted as further evidence that the efferent vessel of the glomerulus is subject to the constricting action of adrenalin.

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