Urinary Myoglobin in Myocardial Infarction

Publisher Website
Google Scholar
Abstract
To the Editor:— This study was undertaken to determine whether analysis for myoglobin in consecutive urine specimens was sufficiently helpful in the diagnosis of myocardial infarction to displace current serum enzyme studies. In addition, we wanted information indicating its value to the clinician as an additional testing procedure in acute myocardial infarction. Methods.— At the start of the experiment, the first urine specimens were collected from all patients admitted to the intensive care ward of the Elkhart (Ind) General Hospital regardless of the diagnosis. Later, when it became apparent that the first specimen did not necessarily contain the most myoglobin, all urine was collected only from patients with suspected myocardial infarction. Antiserum to human myoglobin in the rabbit was prepared as described by Rozman et al,1 and Rozman and Adams.2 Conjugates of myoglobin covalently linked to formalinized sheep erythrocytes were prepared as described by Adams and Rozman.3

This publication has 0 references indexed in Scilit: