4-Substituted 2-Phenyl- and 2-Phenyl-3-Aryl Pyrroles by Reaction of Tosyl Benzyl Isocyanide (TosBIC) with Michael Acceptors
- 1 March 1995
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 25 (6) , 795-802
- https://doi.org/10.1080/00397919508013415
Abstract
Synthesis of 2-phenyl and 2,3-diphenylpyrroles bearing at the 4 position electronwithdrawing groups by reaction of tosylbenzylisocyanide (TosBIC) with various Michael acceptors was investigated. Sodium hydride and n-butyllithium were used as deprotonating agents for the synthesis of monophenyl and diphenylpyrroles, respectively.Keywords
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