Abstract
To the Editor: In the August 23 issue of the Journal, Descos et al. report that serum levels of β2-microglobulin correlate with activity in Crohn's disease.1 They consider follow-up studies to be necessary to determine whether elevations of serum levels of β2-microglobulin can be regarded as an indicator of relapse.We have studied serum levels of β2-microglobulin in 36 patients with Crohn's disease (one to four determinations one to nine months apart). The study comprised 20 male and 16 female patients between 21 and 67 years of age (mean age, 32 years). Crohn's . . .

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