Elimination of an abnormal cell line from blood lymphocytes during post‐natal growth
- 1 June 1980
- journal article
- research article
- Published by Wiley in Clinical Genetics
- Vol. 17 (6) , 433-436
- https://doi.org/10.1111/j.1399-0004.1980.tb00176.x
Abstract
A cell line carrying an additional metacentric chromosome of unknown origin was present in PHA[phytohemagglutinin]-stimulated blood lymphocytes from a newborn female. The child had no marked physical or developmental abnormality but was small. The abnormal cell line, present in 20% of blood cells at birth, progressively decreased and was absent by 16 mo. Loss of the cell line appeared to involve a process of elimination rather than a chance event.Keywords
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