Quantitative and Qualitative Impairment of lmmunoregulatory Cells in the Circulation of Rheumatoid Arthritic Patients
- 31 December 1983
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Rheumatology
- Vol. 13 (2) , 155-162
- https://doi.org/10.3109/03009748409100380
Abstract
T cells bearing receptors for the Fc portion of IgM or IgG, TM or TG cells respectively, in the peripheral blood of RA and OA patients were found significantly less often when compared with TM and TG cells in the peripheral blood of normal donors. Using culture combinations of TM, TG and B cells, we were able to demonstrate that the B cells in the peripheral blood of RA patients were constantly of low functional competence and the TM cells vaned between highly competent and low competent. RATG cells in general suppressed normal B-lymphoblast differentiation.This publication has 23 references indexed in Scilit:
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