Competition Controls the Growth of an Identified Axonal Arborization
- 22 June 1984
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 224 (4655) , 1352-1355
- https://doi.org/10.1126/science.6729457
Abstract
The shape of the axonal arborization was studied in an identified insect sensory neuron. The distribution of presynaptic varicosities within an axonal arbor was shown to be modulated by the density of neighboring terminals. Removal of neighbors near one portion of the axon terminal increased the growth rate in the denervated region and caused a compensatory retraction in other regions. The results support the hypothesis that the size of an axonal arbor is determined intrinsically, whereas the distribution of varicosities within the terminal is determined extrinsically by neighboring terminals. These findings provide a direct demonstration of the effects of competition on an identified nerve cell, as well as one of the first examples of competitive interactions in an invertebrate central nervous system.This publication has 25 references indexed in Scilit:
- Effects of monocular deprivation on geniculocortical synapses in the catJournal of Comparative Neurology, 1984
- The regulation of synapse formation in the fly's visual systemTrends in Neurosciences, 1983
- Modulation of neuronal competition by postsynaptic geometry in autonomic gangliaTrends in Neurosciences, 1983
- A topographic map of sensory cell terminal arborizations in the cricket CNS: Correlation with birthday and position in a sensory arrayJournal of Comparative Neurology, 1980
- Plasticity of retinofugal projections after partial lesions of the retina in newborn syrian hamstersJournal of Comparative Neurology, 1979
- Expansion of the half retinal projection to the tectum in goldfish: An electrophysiological and Anatomical studyJournal of Comparative Neurology, 1978
- The shapes of sensory and motor neurones and the distribution of their synapses in ganglia of the leech: a study using intracellular injection of horseradish peroxidaseProceedings of the Royal Society of London. B. Biological Sciences, 1976
- Deafferentation slows the growth of specific dendrites of identified giant interneuronsJournal of Comparative Neurology, 1975
- The cerci and abdominal giant fibres of the house cricket, Acheta domesticus . I. Anatomy and physiology of normal adultsProceedings of the Royal Society of London. B. Biological Sciences, 1974
- The cerci and abdominal giant fibres of the house cricket,Acheta domesticus. II. Regeneration and effects of chronic deprivationProceedings of the Royal Society of London. B. Biological Sciences, 1974