Histamingehalt des Sputums von Patienten mit chronisch obstruktiver Bronchitis

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Abstract
Sputa of patients with chronic obstructive lung disease show high histamine concentrations with large individual variations. The fluorometric and biologic method correlate statistically significantly. Histamine concentrations decrease significantly during 60 min at 37.degree. C, by different amounts in different patients. The measured histamine concentration can cause bronchoconstriction. Histamine and the NaCl control solutions have been found to liberate histamine into the blood, measured as free plasma histamine.
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