Eudismic analysis of a series of muscarinic ligands carrying a 1,3‐oxathiolane nucleus
- 1 January 1990
- Vol. 2 (2) , 79-84
- https://doi.org/10.1002/chir.530020204
Abstract
Eudismic analysis was performed on a set of 14 muscarinic ligands carrying a 1,3-oxathiolane nucleus, in order to obtain information about both the existence of receptor subgroups and of agonist and competitive antagonist interaction sites. The results obtained were compared with those from a study of the enantioselectivity of the pairs of enantiomers. The two approaches do not appear to be completely equivalent and would seem to complement each other usefully.Keywords
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