Lipase-mediated synthesis of the enantiomeric forms of 4,5-epoxy-4,5-dihydro-α-ionone and 5,6-epoxy-5,6-dihydro-β-ionone. A new direct access to enantiopure (R)- and (S )-α-ionone
- 1 January 1999
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 3,p. 271-278
- https://doi.org/10.1039/a808780f
Abstract
Stereoselective lipase-mediated esterifications of epoxy-α-ionol 5 and epoxy-β-ionol 9 afforded suitable precursors of the enantiomers of the corresponding oxidised derivatives epoxy-α-ionone 3 and epoxy-β-ionone 4. An interesting development of this work is the easy conversion of enantiopure 3a and 3b into highly valuable enantiopure (S)- and (R)-ionone (1a and 1b) via a mild deoxygenation reaction.Keywords
This publication has 0 references indexed in Scilit: