Suitability of controlled release delivery system for root canal disinfection

Publisher Website
Google Scholar
Abstract
The purpose of the present study was to assess the bacteriologic status of the root canal after disinfection with a quaternary ammonium compound in a controlled release system. Root canal infection was induced in 57 single root teeth in dogs. The canals were then instrumented under aseptic conditions and irrigated with sodium hypochlorite and sterile saline. After the instrumentation, 10 canals were treated with the quaternary ammonium compound in the controlled release system, 9 canals with the quaternary ammonium compound on a cotton pellet, 10 canals with formocresol, 10 canals with a paste of calcium hydroxide. In 18 canals, no intracanal medicament was used. Bacteriologic samples were taken after 14 days using an anaerobic technique. The results indicated that the quaternary ammonium compound in the controlled release system was as effective as formocresol and calcium hydroxide in rendering the root canal free of bacteria. The advantages of an antiseptic with a long‐lasting effect for the elimination of bacteria from the root canal and for the prevention of culture reversals were stressed.