Double inversion recovery improves water suppression in vivo

Abstract
It is shown that double inversion recovery used for water suppression can be made much less sensitive to pulse imperfections and to the variations in the relaxation times than a single inversion recovery. This insensitivity results in up to 10‐fold improvement in the water suppression in vivo. The excellent water suppression by double inversion recovery is demonstrated experimentally by the in vivo proton spectra obtained from a rat brain.