Effect of anthrax toxin on oxidative metabolism of lung tissues
- 1 June 1966
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 210 (6) , 1313-1315
- https://doi.org/10.1152/ajplegacy.1966.210.6.1313
Abstract
The O2 consumption quotient (Qo2) of lung brei prepared from control rats and rats that have been injected intravenously with growth medium containing anthrax toxin was measured. A 30% decrease occurs in the tissues of the experimental animals. When a-ketoglutarate is used as a substrate, no relative change occurs. However, added succinate brings the experimental Q02 essentially up to control values. It is postulated that diphosphopyridine nucleotide-dependent enzymes were affected.This publication has 7 references indexed in Scilit:
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