A COMPARISON BETWEEN DEHYDRATION FROM SALT LOSS AND FROM WATER DEPRIVATION

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Abstract
Two human subjects, dehydrated by means of constant Miller-Abbott tube jejunal suction, lost an average of 23 grams of NaCl in 4.5 days and manifested progressive wt. loss, hemoconc, weakness, apathy, anorexia, hypotension, and orthostatic fainting. Thirst and oliguria did not occur. Salt-free water did not remedy the condition, but Ringer''s soln. resulted in prompt recovery. Two human subjects dehydrated by means of simple water deprivation manifested wt. loss, marked thirst, oliguria, azotemia, and no significant hemoconc. Adm. of distilled water resulted in complete recovery. In human subjects, just as previously demonstrated by Kerpel-Fronius in rabbits, there are 2 distinct types of dehydration which differ from each other in mechanism of production, in manifestations, and in the treatment indicated.