Use of cholestyramine in treatment of children with familial hypercholesterolaemia
- 1 May 1973
- journal article
- research article
- Published by BMJ in Archives of Disease in Childhood
- Vol. 48 (5) , 370-374
- https://doi.org/10.1136/adc.48.5.370
Abstract
19 children with heterozygous familial hypercholesterolaemia have been treated with cholestyramine administered twice daily in a total dosage of 8 to 24 g/day (0·3 to 1·1 g/kg body weight per day). Serum cholesterol concentration was reduced by a mean of 36% (range 27 to 47%). The therapeutic effect was similar whether or not dietary fat was restricted, and the reduction in serum cholesterol has been maintained for periods of up to 20 months.Keywords
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