The Ubiquitin System for Protein Degradation and Some of Its Roles in the Control of the Cell‐Division Cycle (Nobel Lecture)
- 14 September 2005
- journal article
- review article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 44 (37) , 5932-5943
- https://doi.org/10.1002/anie.200501724
Abstract
Protein breakdown is an exact, controlled process in which the protein molecule ubiquitin plays a decisive role by binding to a protein and labeling it for breakdown. The cellular mechanisms of this process are widely known today thanks to the work of the 2004 Nobel Laureates Irwin Rose, Avram Hershko, and Aaron Ciechanover. The Laureates report at first hand in their Nobel Lectures. chemical structure imageKeywords
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