Opiate Antagonists and the Modification of Heroin Self-Administration Behavior in Man: An Experimental Study
- 1 January 1976
- journal article
- research article
- Published by Taylor & Francis in International Journal of the Addictions
- Vol. 11 (3) , 485-499
- https://doi.org/10.3109/10826087609056165
Abstract
The heroin self-administration behavior of 8 inpatient heroin addicts was examined for 10 days under blocked (i.e., following ingestion of narcotic antagonists naloxone or naltrexone) and unblocked (no antagonist) conditions. In the unblocked state, subjects injected all the available heroin, but ceased heroin use almost completely following antagonist administration. Possible explanations for these results are discussed along with their implications for treatment.This publication has 7 references indexed in Scilit:
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