The m/z 91 rearrangement ion in the mass spectra of some 1,4‐benzodiazepines
- 1 May 1979
- journal article
- research article
- Published by Wiley in Journal of Mass Spectrometry
- Vol. 14 (5) , 233-238
- https://doi.org/10.1002/oms.1210140502
Abstract
With the aid of isotope labeling and by substituent shifts, the relatively strong m/z 91 ion in the mass spectra of 7‐chloro‐2‐methoxy‐5‐phenyl‐3H‐1,4‐benzodiazepine and related compounds was shown to contain the 5‐phenyl ring and the 3‐CH2 group. Mechanisms involving the opening of the 7‐membered ring and the migration of the phenyl ring from C‐5 to C‐3 are postulated for the formation of this ion. This rearrangement ion was also observed in the mass spectra of some 1‐alkyl‐7‐chloro‐1,3‐dhydro‐5‐phenyl‐2H‐1,4‐benzodiazepin‐2‐ones.Keywords
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