IMMUNOLOGIC IDENTIFICATION OF BOTH PLASMA AND HUMAN RENAL INACTIVE RENIN AS PRORENIN
- 1 February 1985
- journal article
- other
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 60 (2) , 399-401
- https://doi.org/10.1210/jcem-60-2-399
Abstract
Antibodies were raised against a synthetic tetradecapeptide which is a component of the non-renin portion (prosegment) of human renin precursor. Inactive renin from human kidney and plasma strongly adsorbed to a gel coupled to immunoglobulins purified from such an antiserum. These results suggest that renal and circulating inactive human renins contain in their structure the prosegment of prorenin.Keywords
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