Alterations in cat skeletal neuromuscular junctions following prolonged inactivity.

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Abstract
The distributions of acetylcholine (ACh) receptors, cholinesterase (ChE) activity and nerve terminals were studied on cat muscle fibers which had been inactive for 2-3 yr. Neuromuscular junctions increased in size as a result of sprouting of terminal branches. Some fibers were multiply innervated at separate sites. In muscles from 2 cats, some areas at the junction showed ChE activity but had only a relatively low density of ACh receptors. The extrajunctional receptor density was higher than in normal muscles but lower than in muscles denervated for up to 10 mo.