Sequence of a Drosophila segmentation gene: protein structure homology with DNA-binding proteins
- 1 July 1984
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 310 (5972) , 25-31
- https://doi.org/10.1038/310025a0
Abstract
Mutations in the fushi tarazu (ftz) locus of Drosophila result in embryos with half the usual number of body segments. The sequences of the wild-type gene, a temperature-sensitive allele and a dominant mutant allele are presented. A portion of the conserved protein domain present in ftz and several homoeotic genes resembles the DNA-binding region of prokaryotic DNA-binding proteins, and is also similar to products of the yeast mating-type locus.Keywords
This publication has 37 references indexed in Scilit:
- Analysis of larval segmentation in lethal genotypes associated with the Antennapedia gene complex in Drosophila melanogasterPublished by Elsevier ,2004
- Defects in embryogenesis in mutants associated with the antennapedia gene complex of Drosophila melanogasterDevelopmental Biology, 1984
- A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexesNature, 1984
- The molecular organization of the Antennapedia locus of drosophilaCell, 1983
- Molecular Genetics of the Bithorax Complex in Drosophila melanogasterScience, 1983
- Comparison of initiation of protein synthesis in procaryotes, eucaryotes, and organelles.Microbiological Reviews, 1983
- Structure of the cro repressor from bacteriophage λ and its interaction with DNANature, 1981
- Mutations affecting segment number and polarity in DrosophilaNature, 1980
- A gene complex controlling segmentation in DrosophilaNature, 1978
- PSEUDOALLELISM AND GENE EVOLUTIONCold Spring Harbor Symposia on Quantitative Biology, 1951