Genetics of Insulin-Dependent Diabetes; Non-Major Histocompatibility Genes
- 1 June 1996
- journal article
- conference paper
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 28 (06) , 289-293
- https://doi.org/10.1055/s-2007-979795
Abstract
Recently, the major advances in understanding the genetics of type 1 diabetes have come using the positional cloning approach, both in mouse and human. Construction of congenic mouse strains and, in human, the exploitation of linkage disequilibrium between very closely linked markers and disease-predisposing loci, is enabling fine mapping of these loci.Keywords
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