SELF-MAINTENANCE ABILITY AND KINETICS OF HAEMOPOIETIC STROMA PRECURSORS

Publisher Website
Google Scholar
Abstract
The use of repeated femoral curettages and repeated passages of ectopic hemopoietic foci has demonstrated the capacity of stromal precursor cells for repeated formation of hemopoietic microenvironment. During this process the stromal precursors undergo no less than 10-12 mitoses. Precursors of bone marrow stroma proliferating slowly, if at all, in normal mice are triggered into cell cycle, as revealed by suicide methods, during formation of the ectopic hemopoietic focus.