Simultaneous Bioreaction and Separation by an Immobilized Yeast Membrane Reactor

Abstract
The need for immobilized whole cell reactor systems is widely recognized. Many reactor configurations have been tried using one or more semipermeable membranes to perform bioreaction and separation simultaneously (1–3). The major problems faced by such systems are high diffusional resistances, substrate depletion, and product inhibition. Over the past few years many membrane reactors have been proposed which address these problems individually (4, 5).

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