Predicting outcome of antipsychotic drug treatment from early response
- 1 September 1980
- journal article
- research article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 137 (9) , 1088-1089
- https://doi.org/10.1176/ajp.137.9.1088
Abstract
Newly admitted schizophrenic patients [48] were given an initial test dose (2.2 mg/kg) of chlorpromazine hydrochloride and additional doses at 24 and 36 h. Clinical response was measured at 48 h and at the end of 28 days of subsequent treatment with a fixed dose (6.6 mg/kg) of chlorpromazine. There was a consistent correlation between 48 h change and the eventual amount of improvement by the end of drug treatment for all 10 outcome criteria. Change early in drug treatment is a useful predictor of outcome.This publication has 0 references indexed in Scilit: