A Fungicidal Monoclonal Antibody Protects against Murine Invasive Candidiasis
- 1 May 2006
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 74 (5) , 3042-5
- https://doi.org/10.1128/iai.74.5.3042-3045.2006
Abstract
Mice infected by Candida albicans and treated with monoclonal antibody C7 survived longer than saline-treated animals. A prozone-like effect was observed. The in vitro candidacidal activity of macrophages was strongly enhanced when C. albicans was opsonized by C7 and complete murine serum was present.Keywords
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