The spread of HIV-1 in Africa: sexual contact patterns and the predicted demographic impact of AIDS
- 1 August 1991
- journal article
- Published by Springer Nature in Nature
- Vol. 352 (6336) , 581-589
- https://doi.org/10.1038/352581a0
Abstract
The spread of HIV-1 in Africa is examined here in the light of recent information on the main epidemiological and behavioural determinants of transmission. Mathematical models incorporating demographic, epidemiological and behavioural processes are used to assess the potential demographic impact of the disease AIDS. These analyses highlight the significance of patterns of sexual behaviour, and in particular networks of sexual contact, on the predicted spread of infection. Current data reveal substantial variations in the degree of spread between and in countries, but new analyses support earlier predictions that in the worst-afflicted areas AIDS is likely to change population growth rates from positive to negative values in a few decades.Keywords
This publication has 49 references indexed in Scilit:
- Sexual lifestyles under scrutinyNature, 1990
- AIDS incubation in 1891 HIV seroconverters from different exposure groupsAIDS, 1990
- The evolutionary dynamics of HIV-1 quasispecies and the development of immunodeficiency diseaseAIDS, 1990
- AIDS—the Leading Cause of Adult Death in the West African City of Abidjan, Ivory CoastScience, 1990
- Perinatal transmission of HIV-I in Zambia.BMJ, 1989
- Perinatal Transmission of the Human Immunodeficiency Virus Type 1 to Infants of Seropositive Women in ZaireNew England Journal of Medicine, 1989
- HIV-1 Infection Among Intravenous Drug Users in Manhattan, New York City, From 1977 Through 1987Published by American Medical Association (AMA) ,1989
- Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDSScience, 1984
- Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)Science, 1983
- Pneumocystis cariniiPneumonia and Mucosal Candidiasis in Previously Healthy Homosexual MenNew England Journal of Medicine, 1981