Pneumonic Plague
- 1 May 1948
- journal article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine
- Vol. s1-28 (3) , 361-371
- https://doi.org/10.4269/ajtmh.1948.s1-28.361
Abstract
Summary 1. A case of proven primary pneumonic plague, resulting from laboratory infection, has been reported. 2. Recovery has taken place after a stormy and protracted course following combined therapy with sulfonamides and streptomycin. 3. In vitro studies on the chemotherapeutic action of sulfadiazine and streptomycin on P. pestis have indicated that streptomycin is more efficacious and that there is some synergistic effect when the two drugs are used in combination. 4. Transfusion malaria and jaundice (either homologous serum jaundice or infectious jaundice) have been observed in this case. 5. Oral sulfadiazine has been used in the prophylaxis of contacts. No secondary case has appeared among them.Keywords
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