PRECIPITATING ANTIBODY IN HUMAN SERUM TO AN ANTIGEN PRESENT IN CULTURED BURKITT'S LYMPHOMA CELLS

Abstract
Sera from 352 individuals were tested for precipitating antibody to antigen prepared from an established line of cultured Burkitt''s lymphoma cells. Two groups of patients showed a high incidence of positive reactions, those with Burkitt''s lymphoma, 31/55 African cases, and those with carcinoma of the postnasal space, 33/39 cases (19 African and 20 American). An incidence of approximately 11% positive reactions was observed among 258 sera (52 African and 206 American) obtained from normal donors, patients with malignant neoplastic diseases of other types, and patients with nonneoplastic diseases.