Epstein-Barr Virus in an American Patient With Burkitt's Lymphoma: Detection of Viral Genome in Tumor Tissue and Establishment of a Tumor-Derived Cell Line (NAB)2
- 1 April 1976
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 56 (4) , 701-704
- https://doi.org/10.1093/jnci/56.4.701
Abstract
Epstein-Barr virus (EBV) DNA (17.7 genome equivalents/cell) was found in tumor tissue from an American patient with Burkitt's lymphoma who had never traveled outside the United States. A lymphoid cell line (NAB) containing the EBV genome was established from tumor tissue from this patient; characteristics of this cell line were described. Previous Burkitt's tumors found in Americans and examined by molecular hybridization were negative for EBV DNA. Our results suggested that EBV is associated with at least some American Burkitt's tumors.Keywords
This publication has 2 references indexed in Scilit:
- Immunofluorescence in Cells Derived from Burkitt's LymphomaJournal of Bacteriology, 1966
- Childhood lymphoma resembling “burkitt tumor” in the United StatesCancer, 1965