HEMOGLOBINS .21. SEQUENCE-ANALYSIS OF PORCINE HEMOGLOBIN

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  • 1 January 1978
    • journal article
    • research article
    • Vol. 359  (2) , 137-146
Abstract
The Hb of a bavarian domestic pig (Suidae) was isolated. The chains were separated by countercurrent distribution, then cleaved with trypsin. The isolated peptides were sequenced with hydrophilic phenylisothiocyanate I and IV, or with a dimethylaminopropyne program in the sequenator. The sequences of the chains are given. Some methodical aspects of automatic sequencing are discussed and the sequences of human and porcine Hb are compared. The role of adult pig Hb as a fetal Hb is discussed.