Solitary extramedullary plasmacytoma of the palpebral conjunctiva.

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Abstract
A 63 yr old man had a solitary extramedullary plasmacytoma of the conjunctiva for several years with no history of ocular inflammation or systemic abnormalities. Immunoperoxidase staining was consistent with a neoplastic lesion. Apparently, this is the only well documented case in the recent literature. This rare condition is contrasted with reactive plasma cell granuloma, a benign inflammatory condition, which comprises most of the cases previously reported as plasmacytomas. Since extraskeletal plasmacytomas may be the 1st manifestation of multiple myeloma, these patients deserve appropriate diagnostic evaluation and close follow-up.