Occupational eczema from para‐tertiary‐butylphenol formaldehyde resins: A review of the sensitizing resins

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Abstract
The first cases of allergy due to para‐tertiary‐butylphenol formaldehyde resins (PTBP resins) were found in 195K in the shoe‐making industry. These resins are found in certain neoprene adhesives.PTBP resin hypersensitivity may be due either to the para‐ tertiary‐butylphenol, to the resin itself, or less frequently to the formaldehyde.These resins may cause occupational allergy (in the automobile industry and chiefly in the shoe‐making industry) and non‐occupational allergy (footwear and clothing hypersensitivity).Patients allergic to PTBP resins have been found to show a cross‐reaction to other resins such as Alresen PA 103, Schenectady SP 126 and Schenectady SP 154.The authors give a reference list of sensitizing neoprene adhesives and PTBP resins to that manufacturers can limit the use of these products as far as possible.