ASSAY PROCEDURES FOR CATHEPSIN-B, CATHEPSIN-H AND CATHEPSIN-L ACTIVITIES IN RAT-TISSUE HOMOGENATES

Abstract
Cathepsin B, H and L activities in small amounts of rat tissue homogenates corresponding to 10 .mu.g protein were determined with 7-amino-4-methyl-coumarin conjugates as substrates. A new procedure for serum cathepsin H activity was also developed. High cathepsin B and H activities were found in kidney, spleen and liver. Liver cathepsin B, H and L activities in D-galactosamine-injured rats were decreased concomitantly with an increase in serum cathepsin H activity.

This publication has 13 references indexed in Scilit: