Abstract
A case of acute myelogenic leukemia developing after 7 mo. treatment with alkylating agents for multiple myeloma is reported. The patient was also given irradiation for an expansive process in the thoracic column. By immunofluorescence staining of the bone marrow cells there was no evidence for production of pathological globulins in the blast cells, while the plasma cells contained Ig[immunoglobulin]A-.kappa.

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