Intramolecular general base catalysed alcoholysis of amides
- 1 January 1974
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 14,p. 525-526
- https://doi.org/10.1039/c39740000525
Abstract
The pH-independent cyclization of 3-amino-2-hydroxymethylbenzamide proceeds with intramolecular general base cataysis at a rate103 times greater than that for the 4-, 5-, and 6-amino, or unsubstituted 2-hydroxymethylbenzamide.Keywords
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