Pulmonary Embolism Complicating Trypsin Therapy

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Abstract
THE therapeutic use of trypsin in acute inflammation with rapid subsidence of the process, and the later thrombolytic changes that it produces, has been extensively and admirably studied and discussed by Innerfield, Angrist and Schwarz.† This paper mentions that pulmonary emboli did not develop in any of the patients with thrombophlebitis treated with trypsin. The thought that trypsin, by initiating a fibrinolytic reaction, would prevent embolization was an interesting one, but short lived. In the following case of iliofemoral thrombophlebitis on the left, pulmonary embolism occurred during trypsin therapy.Case ReportR. W., a 40-year-old man, was admitted to the . . .

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