Subendothelial ? 2-adrenoceptors in the rat vena cava: Facilitation of noradrenaline release via local stimulation of angiotensin II synthesis
- 1 October 1986
- journal article
- research article
- Published by Springer Nature in Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie
- Vol. 334 (2) , 156-165
- https://doi.org/10.1007/bf00505816
Abstract
In conclusion, angiotensin receptors and α2-adrenoceptors appear to be located on the sympathetic nerve endings, but a major part of the β2-adrenoceptors probably is subendothelial (most likely on smooth muscle cells). Angiotensin II, synthesized in response to β2-adrenoceptor activation, probably stimulates angiotensin receptors on the noradrenergic nerves, leading to an increase in noradrenaline release.Keywords
This publication has 45 references indexed in Scilit:
- Adrenaline Mediates A Positive Feedback Loop in Noradrenergic Transmission: Its Possible Role in Development of HypertensionClinical and Experimental Hypertension. Part A: Theory and Practice, 1984
- The interactions of prostaglandins with the sympathetic nervous system—a reviewJournal of the Autonomic Nervous System, 1983
- The Effects of Captopril on Rat Aortic Angiotensin-Converting EnzymeJournal of Cardiovascular Pharmacology, 1982
- Renin substrate in rat mesenteric arteryCanadian Journal of Physiology and Pharmacology, 1981
- Angiotensin I converting enzyme activity in portal vein studied in normotensive rats and in models of primary and secondary hypertensionActa Physiologica Scandinavica, 1981
- On the stereospecificity of the β2-adrenoceptor blocking properties of prenalterolJournal of Pharmacy and Pharmacology, 1980
- Vascular renin-like activity and blood pressure maintenance in the rat. Studies of the effect of changes in sodium balance, hypertension and nephrectomy.Hypertension, 1979
- Presynaptic receptor systems on the noradrenergic neurones of the rabbit pulmonary arteryNaunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie, 1977
- β2-Adrenoceptors Facilitating Noradrenaline Secretion from Human Vasoconstrictor NervesActa Physiologica Scandinavica, 1976
- Differentiation of Receptor Systems activated by Sympathomimetic AminesNature, 1967