Atrophy of Leydig cells in the testes of men with longstanding chronic bronchitis and emphysema.
Open Access
- 1 August 1987
- Vol. 42 (8) , 615-619
- https://doi.org/10.1136/thx.42.8.615
Abstract
The total volume of Leydig cells in the testes of men coming to necropsy with a history of chronic bronchitis and emphysema of at least 15 years' duration, and with morphological evidence at necropsy of the cardiopulmonary effects of hypoxia, was significantly less than the volume in matched controls (0.98 (SD 0.39) and 0.93 (0.42) ml v 1.66 (0.54) and 1.72 (0.52) ml for left and right testes respectively; p less than 0.005). This atrophy may be a consequence of hypoxic inhibition of pituitary synthesis or release of luteinising hormone.This publication has 16 references indexed in Scilit:
- Effects of hypobaric hypoxia on the Leydig cell population of the testis of the ratJournal of Endocrinology, 1984
- Hypoxia, depression of testosterone, and impotence in pickwickian syndrome reversed by weight reduction.BMJ, 1984
- Sex hormone suppression and sexual impotence in hypoxic pulmonary fibrosis.Thorax, 1984
- Endocrine and metabolic studies in unstable cor pulmonale.Thorax, 1983
- Hypothalamic-pituitary dysfunction in respiratory hypoxia.Thorax, 1981
- Effect of Acute and Chronic Simulated High Altitude on Male Reproduction and Testosterone LevelArchives of Andrology, 1980
- Diet, absorption, and hormone studies in relation to body weight in obstructive airways disease.Thorax, 1979
- Total leydig cell volume and its estimation in dogs and in models of testisThe Anatomical Record, 1972
- ESTIMATION OF THE VOLUME OF LEYDIG CELLS IN MANThe Lancet, 1969
- Histometric assessment of human testicular biopsiesThe Journal of Pathology, 1969