The Determination of N-Methylformamide and N-Methylacetamide in Urine
- 1 February 1974
- journal article
- research article
- Published by Taylor & Francis in Aihaj Journal
- Vol. 35 (2) , 84-87
- https://doi.org/10.1080/0002889748507009
Abstract
N-methylformamide (MMF) and N-methylacetamide (MMAC), the principal metabolites of dimethylformamide and dimethylaceitamide, when present in urine in concentrations between 5 and 500 µl/liter can be measured by direct injection of an aliquot of a specimen on a Chromosorb 103 column of a gas chromatograph. The sensitivity of the method can be increased to measure 0.3 µl/liter of MMAC or 0.5 µl/liter of MMF by chromatographing dichloromethane extracts of concentrated urine residues.Keywords
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