Biosynthesis of Lycopodine. The Question of the Intermediacy of Piperidine-2-acetic Acid

Abstract
In Lycopodiumtristachyum lycopodine is derived from L-lysine whereas pipecolic acid is derived from D-lysine. Malonic acid serves as a specific precurser of the non-lysine derived segments of lycopodine. Piperidine-2-acetic acid is not incorporated into the alkaloid.

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