LIPOPROTEIN AND ALBUMIN ACCUMULATION IN REENDOTHELIALIZED AND DEENDOTHELIALIZED AORTA
- 1 January 1984
- journal article
- research article
- Vol. 114 (1) , 112-120
Abstract
Although arterial injury is believed to be an important factor in the pathogenesis of atherosclerosis, little is known about lipoprotein accumulation in the injured arterial wall. The accumulation of iodinated lipoprotein and albumin was quantitated in reendothelialized and deendothelialized rabbit aorta. Over the experimental period, insudated lipoprotein but not albumin is retained in the reendothelialized aorta. Neither lipoprotein nor albumin was retained in the adjacent persistently deendothelialized aorta. Findings are consistent with the hypothesis that sequestration of lipoprotein in reendothelialized artery is one mechanism by which lipid accumulates in these areas.This publication has 40 references indexed in Scilit:
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